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215 NF-B promotes EndMT in PAH In a study involving rats with MCT-PAH, it was shown that the increased expression of EndMT-associated molecules, including N-cadherin, vimentin, Snail, and Slug, was partially attributed to the activation of the NF-B pathway

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CD40-mediated immune cell activation enhances response to anti-PD-1 in murine intrahepatic cholangiocarcinoma

Immunofluorescence analysis was done in a blinded way when possible, as was analysis of metabolomics experiments

We continued to interfere with the pathway mediated by erucamideTMEM19 in rd10 mice by using neutralizing antibodies for the downstream angiogenic and neurotrophic factors of VEGFA, FGF-2 and TNF, which were found to be regulated by erucamide both in the MPCs and in vivo CD11b + cells, to test if these factors are the downstream agents of erucamide rescue in degenerating retinas