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Although VEGF-D is a potential biomarker for ramucirumab in colorectal and hepatocellular carcinoma, earlier studies did not identify it as a useful biomarker for patients with GC (156)

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Folinic acid (Leucovorin) is the preferred form of folate for addressing low brain folate in autism because it bypasses folate receptor blockade and provides a usable form of folate without requiring conversion by DHFR