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Mutagenesis In the published literature, acetaminophen has been reported to be clastogenic when administered at 1,500 mg/kg/day to the rat model (3.6-times the MHDD, based on a body surface area comparison)

Moreover, the opposite changes of several genera have also been reported in different studies

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Dietary protein level and aflatoxin B1-induced preneoplastic hepatic lesions in the rat. J