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Down-stream, dendritic cells exposed to smoke migrate poorly to lymph nodes and bias T-cell priming away from protective Th1 immunity, favouring Th2, Th17, and regulatory T-cell profiles marked by exhaustion receptors such as PD-1 and CTLA-4 (Feng et al., 2011

Cancer alters the metabolic fingerprint of extracellular vesicles

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Carnitine supplementation to obese Zucker rats prevents obesity-induced type II to type I muscle fiber transition and favors an oxidative phenotype of skeletal muscle