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The lyophilized cake is stable for 24+ months at 4 C

Similarly, an antibiotic trial in AD aimed at altering the microbiome did not yield cognitive improvement over placebo [284, 285]

Systemic infections and inflammation affect chronic neurodegeneration

Currently, it is believed that oxidative stress has a significant negative impact also on inflammatory diseases, cancer, ischemic diseases, immunodeficiency syndrome, hypertension, alcoholism, smoking-related diseases, and many others [56,57,58,59,60,61]