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No serious acromegaly, hypoglycemia, or excessive IGF1 elevations reported at recommended dosages (builtin negative feedback prevents overshooting)

She was initially treated with insulin, but reached good glycemic control (HbA1c 5,7%) with metformin 1.5g/day alone thereafter, with improvement of skin lesions especially on the hands

When researchers looked at more than 20,000 PRP injections over a period of 10 years, they found it wasn't clear whether the results justified the cost

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Key considerations for IM injections include: Using a needle of the right length to ensure the medication is delivered into the muscle Rotating injection sites to avoid muscle irritation Administering the injection at a 90-degree angle to the skin surface Subcutaneous Administration Benefits Subcutaneous injections put Vitamin B12 into the fatty tissue just under the skin