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Vitamin B12 deficiency can occur due to dietary restrictions (vegetarian or vegan diets), absorption issues (pernicious anemia or gut disorders like celiac disease or Crohns disease), age-related changes in elderly patients, or long-term use of certain medicines

Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, Pirinen E, Pulinilkunnil TC, Gong F, Wang YC, Cen Y, Sauve AA, Asara JM, Peroni OD, Monia BP, Bhanot S, Alhonen L, Puigserver P, Kahn BB (2014) Nicotinamide N -methyltransferase knockdown protects against diet-induced obesity

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