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We further examined the protein expression and activation states of Smad2 and Smad3, which are downstream effectors of TGF signaling, in NP cells treated with L929 conditioned media

Running both as independent variables within the same 10mg-scale protocol allows precise pathway dissection that would not be possible with a single compound alone

Subunit vaccines, composed of one or a few mycobacterial antigens delivered with a platform of choice, have better safety profiles than live attenuated vaccines ( MTB ( MTB antigens linked to MHC-I in primary human macrophages sourced from six donors with LTBI ( MTB challenge model