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This review analyzes current evidence on the intricate relationships between MASLD, insulin resistance, and type 2 diabetes mellitus (T2DM), with particular emphasis on gut microbiome interactions

10.1073/pnas.95.16.9562

Gentile V, Vicini P, Prigiotti G, et al

L.TrentzschK.InojosaH.HaaseR.SchrieferD.et al

Alterations of individual TRP catabolism pathways in aging, alcoholism, inflammatory bowel disease, metabolic syndrome, renal insufficiency, liver cirrhosis, cancer, and nervous diseases, e.g., depression, Alzheimers and Parkinsons diseases, multiple sclerosis, and schizophrenia, are examined in the central section