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Description

Overlay histogram showing THP-1 cells stained with A02059-1 (Blue line)

PTEN dephosphorylates AKT to prevent the expression of GLUT1 on plasmamembrane and to limit glucose consumption in cancer cells

By targeting different molecular pathways-mitochondrial dysfunction, miR-144-3p/SLC7A11, and ACSL4-these approaches aim to improve angiogenesis and cell survival, presenting promising options for clinical application