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MartinezJEKahanaDDGhumanSWilsonHPWilsonJKimSCJet al

These pathogens possess choline TMA-lyase activity, enabling the conversion of dietary choline into trimethylamine (TMA), a precursor to TMAO, and exhibit invasive capabilities that allow them to enter and persist within vascular tissues

2007 doi: 10.1152/ajpcell.00115.2007

Moreover, SL improved diet-induced NASH with liver fibrosis by disturbing the role of the inflammatory cytokine and suppressing the activation of HSCs (Kim et al., 2012)