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131 Similarly, sinomenine exhibits hepatoprotective effects through suppression of NLRP3 inflammasome activation, reduction of oxidative stress, and inhibition of the HMGB1/TLR4/NF-B pathway

PLoS One 9 , e113642 (2014)

Fiber resists enzymatic digestion and absorbs liquids in its passage along the intestinal tract and thereby producing bulk, which acts as a stimulant for defecation

Systematic phosphoproteomic analyses further reveal that tinnitus development critically depends on phosphorylation-mediated post-translational modifications that reshape synaptic function, particularly affecting membrane receptors and synaptic proteins (Zhang et al., 2025)

Moreover, NASH patients demonstrated impaired synthesis and excretion of lipoproteins [13, 38], indicating that there is a limited capability of excretion of VLDL particles, which might be secondary to hepatocellular impairment [38, 39]