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Therefore, the effective therapy of many neurodegenerative disorders of the central nervous system (CNS) such as Parkinsons disease (PD) or Alzheimers disease (AD) remains a serious challenge

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Therefore, inhibition of Grx2 would promote glutathionylation of the active site, causing SIRT1 inactivation and prevent angiogenesis [41]

[DOI] [PMC free article] [PubMed] [Google Scholar] 196.Kolovrat M., Gojkovic S., Krezic I., Malekinusic D., Vrdoljak B., Kasnik Kovac K., Kralj T., Drmic D., Barisic I., Horvat Pavlov K., et al