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Common additions: Thymosin Alpha-1 (broader immune modulation), MOTS-C (mitochondrial/metabolic support), or LL-37 (additional antimicrobial)

Anti-Gout/Rheumatic: Methotrexate used for some autoimmune disorders and cancer treatments depletes folic acid

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The first component was a baseline assessment of plasma metabolites of the methionine cycle and transsulfuration pathway from 20 autistic children (8 children from this group where chosen to receive supplementation) and 33 control children

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