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Why senescent cells are resistant to apoptosis: an insight for Senolytic Development

GSTs have emerged as a promising therapeutic target because specific isozymes are overexpressed in a wide variety of tumors and may play a role in the etiology of other diseases, including neurodegenerative diseases, multiple sclerosis, and asthma

Hazama, A., V

Therefore, in addition to the effects of oncogenes and tumor suppressors, the TME also plays a critical role in the complex process of ferroptosis in tumor treatment and tumorigenesis

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