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As of 2023, recreational cannabis consumption is legal in 24 states and medicinal cannabis is available in an additional 17 states in the United States (Marijuana legality by state - Updated Oct 1, 2023

People lose a small but steady amount by gastrointestinal blood loss, sweating and by shedding cells of the skin and the mucosal lining of the gastrointestinal tract

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Hyperoxaluria: High oxalates in the urine increase the risk of calcium oxalate kidney stones

While daily use is possible, most protocols recommend 3-5 times weekly to reduce potential tolerance development