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2.3 The synergistic network of microbial metabolites: integrating short-chain fatty acids and tryptophan derivatives 2.3.1 Short-chain fatty acids and their immunomodulatory effects The impact of the gut microbiota on host physiology is mediated by a complex network of metabolites, among which short-chain fatty acids (SCFAs) and tryptophan-derived indoles represent two pivotal communicative channels

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Summary Coronary Heart Disease (CHD) is a leading cause of heart attack and death worldwide

furthermore, it is the acid-resistant gene controlling acid resistance mechanisms (Ma et al., 2012)