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Description

At the cellular level, stress-induced IL-6 activation leads to elevated reactive oxygen species (ROS) and inhibition of mitochondrial cytochrome c oxidase by nitric oxide

These agents work by blocking de novo fatty acid synthesis, thereby limiting membrane biosynthesis, signaling lipid production, and energy storage

W.LouY.et al (1999)

The MITE lentiviral library was stably transduced into p53-null ovarian cancer cell lines, SKOV3 and OVCAR5, and transduced cells were selected for using puromycin (Fig