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Additionally, polyphenols interact with other neurotransmitter systems, including dopamine and noradrenaline, which play crucial roles in motivation, pleasure, and cognitive function [215, 216]

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Nrf2 is a key transcription factor with a basic-region leucine zipper (bZIP) structure in the Cap-n-Collar (CNC) family, which controls many aspects of cell homeostasis in response to oxidative stress and toxic insults in various tissues and cells (Skibinski et al., 2017