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Branching morphogenesis assay RPTEC (2 10 4 cells) were suspended in 400 l Cellmatrix type IA collagen solution (Nitta Gelatin) in a 48-well plate and allowed to gel for 60 min at 37 C, according to the manufacturers instructions

Per its FDA label, tesamorelin has a mean elimination half-life of roughly 18 minutes after a single subcutaneous dose and about 37 minutes with multiple dosing

[0350] Various delivery systems are known and can be used to administer the pharmaceutical compositions described herein, e.g., encapsulation in liposomes, microparticles, microcapsules, recombinant cells capable of expressing the mutant viruses, receptor mediated endocytosis (see, e.g., Wu et al., 1987, J