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In fact, it has been reported that oxidative stress induces ER stress and the unfolded protein response (UPR) in lens epithelial cells, ultimately resulting in apoptosis 44

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Interestingly, BPTES also accelerated the production of pro-inflammatory cytokines produced by M1-like macrophages and boosted the immune responses [77, 78]

Once ingested, gastric enzymes and hydrochloric acid hydrolyze the peptide before it can reach the bloodstream intact, eliminating its ability to stimulate the pituitary gland

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