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Macrocytic anemia occurs when your body doesnt have enough normal red blood cells, and can cause symptoms including muscle weakness and paresthesias (paresthesias is the technical term for the pins and needles feeling on your skin)

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[8] One such potential pathway involves the activation of phospholipase C (PLC), which researchers suggest may lead to the release of inositol triphosphate (IP3) and diacylglycerol (DAG)

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