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Most of the oxidative species that are formed in the CNS are secondary to oxidative phosphorylation (Karam et al., 2017) and mitochondrial dysfunction is the largest source of ROS production, so is a clear sign of affectation of motor neurons in the spinal cord and the motor cortex (Kawahara et al., 2004

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Abstract Background: Quercetin, a widespread polyphenolic flavonoid, is known for its extensive health benefits and is commonly found in the plant kingdom

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doi: 10.3389/fncel.2015.00003 Received 25 September 2014 Accepted 05 January 2015 Published 28 January 2015 Volume 9 - 2015 Edited by Tycho M