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The Role of Surgery for Local Consolidative Therapy in the Management of Oligometastatic Disease

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What Happens in Intervertebral Disc Degeneration Intervertebral disc degeneration is characterized by progressive structural and biochemical changes, including: Loss of proteoglycan content Reduced water retention (disc desiccation) Decreased disc height Altered mechanical properties Increased susceptibility to herniation and annular fissures These changes disrupt spinal biomechanics and may contribute to pain, nerve compression, and reduced mobility

Since the human body cant synthesize B-12, we rely largely on food sources and supplements to get the essential B-12 we need for energy metabolism, the production of red blood cells, and more

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