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Notably, xCT-deficient macrophages exhibited an upregulation of pro-inflammatory genes, including IL-1 and TNF-

doi:10.1016/S0040-4039(98)00455-9 Parales JV, Parales RE, Resnick SM, Gibson DT (1998) Enzyme specificity of 2-nitrotoluene 2,3-dioxygenase from Pseudomonas sp