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0.16 ng/ml/12 ml/day till the sacrifice) and intragastrically after cuprizone instilations, while controls received simultaneously drinking water only (12 ml/day) as well as an equivolume of saline (5 ml/kg) intragastrically after cuprizone instillations

Observed findings depend on route, formulation, concentration, and study design

Collectively, our success in establishing Bz-MS demonstrates that DeepCDM is a highly versatile approach generalizable from one class of CDMs to another

Whether via nasal spray (e.g., in the hour before bed) or injection (depending on protocol), aligning it with your nightly routine maximizes the chance of enhancing deep sleep, helping you to fall asleep more easily, and supporting your sleep-wake cycle

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