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Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J

Dietary supplementation with omega-3-PUFA-rich fish oil reduces signs of food allergy in ovalbumin-sensitized mice

66 In contrast, pharmacologic inhibition of FAO with etomoxir or ranolazine inhibited cancer cell proliferation and sensitized human leukemia cells to apoptosis induced by ABT-737, a molecule that released proapoptotic Bcl-2 proteins such as Bak from antiapoptotic family members, suggesting that CTP1 can antagonize Bcl-2-induced apoptosis

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however, these findings have not resulted in the development of efficacious drug therapy