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If supportive measures such as supplementation, topical therapy, or sun protection are discontinued, pigmentation may gradually recur

This is critical, since even though the amounts of SAA intake closely reflects the rate of sulfate excretion, below a certain level of intake tubular reabsorption of sulfates prevents further loss

Andreeff M , Zhao S, Konopleva M, Xie Z, Zhang X, Snell V, McQueen T, Jiang S, K-O K, Schenk T, Weidner D, Estey E, Thall P, Sanchez-Williams G, Kornblau SM, Reed JC

Pei X, Zhang J, Liu J