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Abstract Metformin is the most prescribed oral hypoglycemic drug and is considered by many health practitioners as the first-line treatment for non-insulin-dependent diabetes mellitus (T2DM)

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Lack of serum B12 levels or methylmalonic acid/homocysteine measurements: The diagnosis of B12 deficiency, although clinically justified, would have been more robust with documented low B12 levels and elevated methylmalonic acid/homocysteine

With just one treatment, the regenerative process is initiated, but the full effect will build gradually over the course of between two to three months

1 Introduction Neuroblastoma (NB) is the most common extracranial solid tumor in infants