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3D Modeling and Printing Background Background Carlos Huerta, MD In the last few decades, three-dimensional (3D) printing has emerged as a rapidly advancing area of research and a practical tool to enhance surgical education and outcomes

Research conducted by Hui-Hui Xiao and colleagues (156) demonstrated that OVX rats exhibited dyslipidemia, abnormal bile acid metabolism, and insulin resistance, which were correlated with an elevated Firmicutes / Bacteroidetes (F/B) ratio a well-recognized biomarker for steroid deficiency-induced metabolic and skeletal disorders

This, in turn, promotes NCOA4-mediated ferritinophagy, resulting in elevated intracellular iron levels and lipid peroxidation, ultimately triggering ferroptosis and contributing to osteoporotic pathology

Chaban, O

Pathogenesis May arise from fixed macrophages (Kupffer cells) attached to the sinusoidal endothelial cells or from circulating macrophages, unless metastasized from other organs (e.g., skin, uterus)