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its deficiency causes the accumulation of low-molecular-weight nitrogen compounds, further impairing plant metabolic processes (Yamamoto et al., 2009)

10.1017/S1041610211000974 Int

However, these may not be salient features of BH4 supplementation in vivo as they appear to be overshadowed by the positive effect generated by alleviating tumor hypoxia

Immunotherapy-Associated Hypothyroidism: Comparison of the Pre-Existing With De-Novo Hypothyroidism