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The present era of anti-angiogenic treatment for cancer research started in 1971 with the publishing of Folkman's creative hypothesis [47], although it would take 33 years for the FDA to authorize the first drug produced as a blocker of angiogenesis

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A cytokine storm is a potentially fatal immune reaction with a positive feedback loop between immune cells and cytokines leading to systemic inflammation that can harm tissues, organs, and systems in the body

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Diagnosis, management and impact of painful diabetic peripheral neuropathy: A patient survey in four European countries