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As a key signaling cascade in insulin-stimulated glycolysis, the PI3K/Akt pathway plays a pivotal role in maintaining glucose homeostasis by enhancing cellular glucose uptake and utilization

Other factors like competition from other amino acids, reduced uptake by cationic amino acid transporters (CATs), and elevated arginase activitycommon in conditions such as hypertension and diabetescan limit L-arginine availability to eNOS, diverting it away from NO production (McDonald et al., 1997a

Histamine derived from probiotic lactobacillus reuteri suppresses TNF via modulation of PKA and ERK signaling

S., Ginger and alpha lipoic acid ameliorate age-related ultrastructural changes in rat liver

For complex formation we incubated the hTrxR1 mutants with NADPH and the respective hTrx1 mutants