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In two multicenter studies of over 1,500 patients requiring NSAID therapy, HZT-501 demonstrated a ~55% reduction in the risk of ulcer (determined by endoscopy) compared to ibuprofen alone over 24 weeks (Laine 2012)

Dosing context: In clinical studies, Thymosin Alpha-1 has been used at 1.6 mg subcutaneous injection twice weekly for 48 weeks in immune reconstitution protocols