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Description

Gayatri B Nair, Harish Gopalakrishna, Ricardo Conti

Kongnyuy, M, Islam, S, Mbah, AK, Halpern, DM, Werneburg, GT, Kosinski, KE, Chen, C, et al

2024;143(Pt 2):113470

The lower bioavailability of NAC after the oral administration and the difference between the reduced and total form are justified by the huge hepatic first-pass effect to which the substance is subject, and by its rapid oxidation, even before reaching systemic circulation