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Description

BMC Cancer 20 , 748 (2020)

Traditional supplementation practices, often characterized by heterogeneous results and variable clinical utility, are increasingly being replaced by evidence-informed frameworks integrating molecular insights, nutrigenomics, and translational trial design

constructed a conditional transgenic mouse model with CPT1A overexpression in tubular EpiCs that was subjected to three models of renal fibrosis

While acknowledging that this was a relatively small retrospective study ( n = 81), the results suggest that in the future, pending further evidence, acetyl-l-carnitine might be considered as an addition to first-line treatments currently recommended by IASP