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Cheraghi E, Soleimani Mehranjani M, Shariatzadeh SMA, Nasr Esfahani MH, Alani B

Interplay between lipid dysregulation and ferroptosis in chondrocytes and the targeted therapy effect of metformin on osteoarthritis

Drug interactions have not been extensively studied, warranting caution when combined with immunomodulatory or anticoagulant medications

304 Studies have shown that hordenine decreases the expression of proinflammatory cytokines by suppressing the S1P/S1PR1/STAT3 pathway and promotes the healing of colonic ulcers by regulating the expression of tight junction proteins, including occludin and ZO-1

Our analysis revealed a surprising overlap between proteins downregulated upon BSO treatment and mitochondrial GSH depletion, suggesting that most of the proteomic changes that occur upon cellular GSH depletion are likely due to mitochondrial effects (Fig