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The overexpression of IGF2 affects the functionality of -cells, leading to chronic endoplasmic reticulum stress and dysfunction of pancreatic islets (216)

The side chain oxygen of the glutamate forms a hydrogen bond with the glycine main chains and has a nonbonded contact with the F H16 side chain (Fig

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Ghrelin is a new endogenous peptide, discovered in 1999 by Kojima et al., as the result of a search for an endogenous ligand for an orphan receptor of known structure and function

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