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10.1021/acsami.1c00583 46 LiY.WenG.LiJ.LiQ.ZhangH.TaoB.et al (2022)

Glia 53, 212224

In addition, targeting of glutathione (GSH) transporters has been used for brain delivery of drugs by prodrugs (Table II)

At the same time, in the culture media of hippocampal neurons, Tamoxifen increased the expression of the anti-apoptotic protein bcl-2, which indicates the neuroprotective effect of the drug