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10:30 - Shawn gets into the biochemistry of caffeine - 1,3,7-trimethylxanthine When you metabolize it -- de-methylate it -- you end up with three other di -methylxanthines

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To facilitate its interaction with the -transducin repeat-containing protein (-Trcp), the Cul1 E3 ubiquitin ligase complex, which negatively controls Nrf2, glycogen synthase kinase-3 (GSK-3) phosphorylates a particular serine residue within the Neh6 domain [28]

Changes in the activity of fatty acid elongation enzymes in plasma and cerebrospinal fluid may play an important role in the development of chronic migraine

Types of carbohydrates called oligosaccharides, raffinose, stachyose and verbascose are present in raw (unsprouted) or poorly processed legumes, which can cause uncomfortable flatulence