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doi: 10.1016/j.celrep.2012.10.013 265 WheaterE

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Several fairly common genetic variants can decrease the function of the GST enzymes, but with several different GST enzymes available, your body usually has a backup route for getting rid of toxicants

For the initial hit validation screen, primary hits were manually picked from the original compound library, while secondary screening assays were performed with compounds that were re-ordered directly from ChemBridge