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PQ generates free radicals through oxidative stress, which can induce dopaminergic neuron death and aggregation of -syn (189)

4, the most abundant differentially abundant microbial genera in the CON group numbered 20, namely Rikenellaceae_RC9_gut_group , Christensenellaceae_R-7_group , UCG_005 , p_251_o5 , UCG_010 , Family_XIII_UCG_001 , NK4A214_group , Saccharofermentans , Bacteroidales_UCG_001 , PeH15 , Eubacterium_brachy_group , Oscillospira , Lachnospiraceae , Lachnospiraceae_UCG_008 , Family_XIII_AD3011_group , PB19 , Pla4_lineage , Lachnospiraceae_UCG_006 , Anaerorhabdus furcosa group, and Desulfovibrio, with Rikenellaceae RC9_gut_group showing the greatest difference in the CON group

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(308) proposed that trained innate immunity is associated with the progression of atherosclerosis

[Google Scholar] [82].Mishima Y, Hozumi S, Shimizu T, et al