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DSIP's action involves: Modulation of Neurotransmitters: DSIP may affect levels of serotonin and norepinephrine, which are involved in mood and relaxation

This approach seeks to address issues related to multiple comparisons, statistical power, population stratification, and failure to replicate from which previous population-based or casecontrol pharmacogenetic association studies may suffer

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Furthermore, a reduction in cortical parvalbumin-positive interneurons, a hallmark of SZ, can also be triggered by NMDAR antagonists 14 , suggesting that they may be particularly vulnerable to NMDAR hypofunction (the relatively young age of the rats used in the current study prevented analysis of parvalbumin-positive interneurons since they are yet to develop)

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