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CAP pathogenesis occurs when bacteria surpass the host's first defensive systems, such as mucociliary clearance of the respiratory tract and alveolar macrophages

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This isoform showed higher enzymatic activity when CDNB and 1,1,1-trichloro-2,2-bis(p-chlorophenyl) ethane and 4-hydroxynonenal were used as substrates, but its IgE-binding frequency was lower (17.9%) compared to the sigma class (20.5%) in cockroach-sensitized patients from Seoul, Korea