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These processes converge into a pathological network defined by the synergistic amplification of iron dysregulation, inflammation, and immune dysfunction

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Elevated serum lactate dehydrogenase (Ldh) should be included among the variables which define high risk multiple myeloma

doi: 10.3389/fphar.2017.00326 165 DistlerJHJungelAPileckyteMZwerinaJMichelBAGayREet al

As reduced GSH is the first line of defense against ROS, its concentration rapidly decreases by oxidant treatment 14 , which may, at least partially, explain the anti-aging effect of mild ROS