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Significant differences exist between animals and humans in gut microbiota: (1) Microbiota composition differences: rodent intestines have similar dominant phyla to humans, but genus-level composition differs significantly

In T2D, therapeutic options, such as dipeptidyl peptidase-4 (DPP-4) inhibitors, incretin-based drugs, and GLP-1 analogues, target -cell function, but not all patients are responsive and approximately 50% ultimately require daily insulin injections due to -cell exhaustion and death (149)

In chicken chorioallantoic embryos, the anti-angiogenic performance of the produced combination was examined

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doi: 10.1001/jamaoncol.2019.6650