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Pharmacopeia (USP) General Chapter 797, Pharmaceutical Compounding

Bacteria-free solution derived from Lactobacillus plantarum inhibits multiple NF-kappaB pathways and inhibits proteasome function

[Crossref] [PubMed] Bump EA, Brown JM

In general, the protective mechanism of L-theanine for the liver and kidney is to inhibit the NF-B pathway, regulate pro-inflammatory cytokines, such as IL-1, IL-6, IL-10, and TNF, and finally regulate the activities of AST, ALT, T-SOD, and other related enzymes, to effectively protect the liver and kidney and deal with liver and kidney injury caused by different reasons

In this study, we developed a mechanistically detailed systems biology model of HGF/Met signaling pathway that incorporated specific interactions with integrins to investigate the efficacy of integrin-binding peptide, AXT050, as monotherapy and in combination with other therapeutics targeting this pathway