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Wound healing demands higher doses than general anti-aging

Over time, you might need injections less often, like every 1-3 months, to keep vitamin B12 levels right

Fidler MisNBraeggerCBronskyJCampoyCDomellfMEmbletonNDet al

doi:10.1016/j.pain.2009.05.020

However, if leptin-deficient obese subjects are studied in parallel with sex and BMI-matched leptin-replete obese subjects, it is found that their GH responses to GHRH and GHRP-6 are equally blunted suggesting that the leptin is not influential in mediating the hyposomatotropinism of obesity (383)