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A large number of studies on the mechanism of AS have revealed that the net effect of immune activation is pro-atherogenic

Proc Natl Acad Sci USA (2000) 97(23):1270510

"S-nitrosothiols signal hypoxia-mimetic vascular pathology"

Exp Neurol (2008) 214:31521.10.1016/j.expneurol.2008.08.015 59 VolkowNDWangGFowlerJSLoganJGerasimovMMaynardLet alTherapeutic doses of oral methylphenidate significantly increase extracellular dopamine in the human brain