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Bidirectional transmission in the GBA plays a major role in modulating brain dysfunction, maintaining symbiosis with the host and modulating innate as well as adaptive immune responses The normal gut microbiota synthesizes microbial metabolites and neurotransmitters that interact with host cells including intestinal epithelial cells (IECs) and immune cells

GSTs are involved in the main detoxification route of AFB1- exo -8,9-epoxide by catalyzing the conjugation of AFB1- exo -8,9-epoxide to endogenous GSH

Just note that the bioavailability and effectiveness of oral capsules compared to injections can vary, and further studies are needed to fully understand this

Morton et al

endothelial, plasma, tissue) and are commonly used in the literature to assess the amount of oxidative stress that is occurring